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This gene encodes a transcription element that belongs to your homeobox gene family. Genes of this family members are hugely conserved between vertebrates and important for vertebrate embryonic enhancement. This gene has been implicated in fetal pores and skin development and cutaneous regeneration.

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In mice, an identical gene was shown to show temporal and spatial colinearity in the leading human body axis on the embryo, but was not expressed within the secondary axes, which my link indicates functions in physique patterning together the axis. This gene as well as other HOXB genes variety a gene cluster on chromosome seventeen within the 17q21-22 location.[6]

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